Oprah’s Star-Packed Farewell!

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Oprah, Patti LaBelle, Dakota Fanning, Halle Berry and Madonna

Madonna said Oprah was one of her role models: "She's been on her game for 25 years, and she's still kicking ass."

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Tom Cruise and Katie Holmes

The couple introduced Rascal Flatts for a performance of "I Won't Let Go."

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Beyonce, Oprah and Dakota Fanning

Wearing a sparkly tuxedo-style bodysuit, Beyonce performed her new single "Run the World (Girls)".

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Jamie Foxx and Oprah

"When I watch the show, I cry because I feel it," Foxx said. "Oprah, thank you for using your gift to lift up so many more."

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Rosie O'Donnell

O'Donnell, backed by Oprah's pals Nate Berkus, Dr. Phil and Dr. Oz, sang about just how much she'll miss the Oprah show.

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Beyonce

Wearing a sparkly tuxedo-style bodysuit, Beyonce performed her new single "Run the World (Girls)".

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Tom Cruise and Oprah

"We got ya!" Cruise said to Oprah of the show's many surprises.

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Tom Hanks, Oprah, Jada Pinkett Smith and Will Smith

"Oprah, I want to thank you for the 25 years you've given us of you. You have enlightened and empowered us, you have taught us how to be. I know you don't have children of your own, but you have mothered millions," Pinkett Smith said. "That puts you in the status of a goddess."

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Aretha Franklin and Oprah

As Winfrey watched in awe, Franklin sang a powerful rendition of "Amazing Grace."

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Gayle King, Oprah and Maria Shriver

Oprah's "best girlfriends" stood proudly by her side. "Over the years, you have shared that very generous spirit. You've believed in others, so they can believe in themselves," Shriver (hours after her estranged husband Arnold Schwarzenegger's shocking revelation of a love child) said.

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Maya Angelou, Alicia Keys and Oprah

Angelou honored Oprah with an original poem. After the reading, Keys performed "Superwoman" on the piano.

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Oprah and Madonna

The longtime pals embraced one another in a hug. "She fights for what she believes in even if it makes her unpopular," Madonna said. "She has balls and a wealth of compassion. I have learned so much from her."

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Halle Berry, Katie Holmes and Queen Latifah

"I loved you the first moment I met you," Berry gushed. The true beauty of your show is that views of your show have risen up to literally change the world."

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Kristin Chenoweth

The Tony Award winner sang "For Good," the song she made famous during her run on Broadway's "Wicked."

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Oprah and Michael Jordan

"It's MJ!" Oprah gushed excitedly when the Chicago Bulls legend appeared.

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Usher

The final surprise guest of the evening sang "Oh Happy Day."