Courteney and David: The Way They Were

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December 1996

"I fell in love with Courteney Cox on Scream," he once said.

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May 1999

He told Howard Stern Oct. 12 that when they first met, she thought his kooky antics were "charming."

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June 1999

They walked down the aisle to Paul McCartney's "Maybe I'm Amazed" in front of guests -- including Brad Pitt and then-wife Jen Aniston! -- at San Francisco's Grace Cathedral.

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November 2003

After a botched Botox procedure, Arquette told Cox to lay off plastic surgery. "He loves the aging process," she's said. "He thinks it's beautiful, [so] I'm under pressure to not do anything."

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January 2004

Shortly before her 40th birthday, Cox welcomed daughter Coco, via in vitro fertilization. Arquette has said they chose the name because "it's sort of an abbreviation of 'COurtney COx'...'CoCo.'"

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January 2007

After Coco's birth, Arquette and Cox considered adoption. "I mean, it takes a lot for us to do it, so maybe," Arquette told The Bonnie Hunt Show earlier in the year.

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April 2007

Arquette and Cox helped Jennifer Aniston recover from a slew of rocky romances. "She's the mother to everyone," he has said of Cox.

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June 2007

The two admitted going to couples therapy. "I get shocked by people getting divorced all the time, that's why I choose to work on it. Therapy helps us," Cox told UK's Daily Mail in 2008.

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April 2009

"Coco's a little messy so that's sort of on my side, but she's very strong-willed which is very Courteney-like," Arquette said on The Bonnie Hunt Show.

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January 2010

"We're not lazy about our marriage," she once told InStyle. "You have to make an effort to stay connected, and that's something we work at."

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June 2010

Four months before announcing their separation, they attended one of their last events together, a 2010 Women In Film function. Despite separating, he has said: "I want her to be happy, more than I want happiness for myself."